AMSTAR represents critical appraisal tools primarily for assessing the methodological quality of systematic reviews of healthcare interventions. The tools can be used for the development and evaluation of reviews; as guidelines for conducting reviews; and as auxiliary aids for teaching systematic reviews.

As one of the key tools in evidence-based medicine, AMSTAR 2 can be used to evaluate systematic reviews that include randomized control trials (RCTs) and/or non-randomized studies of health care interventions (NRSIs). The original AMSTAR tool designed for RCTs was refined to include NRSIs. The resulting AMSTAR 2 tool expanded from 11 to 16 domains retaining 10 of the original domains while the 11th was integrated into another. The response categories are now more concise and are accompanied by a more comprehensive user guide. Overall ratings are based on weaknesses identified across critical domains.

With the help of Artificial Intelligence (AI), and adhering to the internationally recognized AMSTAR 2 standards, this system generates well-structured and highly valid assessment reports in just a few minutes. It intelligently and quickly analyzes which aspects of a systematic review are good and which areas need improvement, helping you swiftly complete evaluations, submit documents and/or conduct self-inspection for your systematic review.